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Additionally, it increases the expression of the peroxisome proliferator-activated receptor (PPAR) and phosphorylated form of AMP-activated protein kinase, improving the regulation of dyslipidemia and increasing lipid metabolism efficiency [130]

Gordon, S.R

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You can find genetic testing with various companies such as 23andme.com Its estimated that those with one mutation (heterozygous) decrease their ability to methylate by 30% and those with two mutations (homozygous) decrease their ability to methylate by 70%, making it virtually impossible to get adequate B12 from diet alone (19)